Italy–South Africa relations are foreign relations between Italy and South Africa. Both countries established diplomatic relations in 1929. Italy has an embassy in Pretoria, a consulate in Johannesburg, 2 consulates (in Cape Town and Durban) and 2 honorary consulates (in East London and Port Elizabeth). South Africa has an embassy in Rome, a general consulate in Milan and 7 honorary consulates (in Bari, Bologna, Florence, Genoa, Naples, Trieste and Venice).
There are around 35,000 people of Italian descent living in South Africa.
During World War II, some 100,000 Italian prisoners of war were held by the British in South Africa.